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At supplemental doses of 500mg-2g/day, this is not considered a significant concern by most researchers

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"The role of glucose and glycosylation in the regulation of lipoprotein lipase synthesis and secretion in rat adipocytes"

The maintenance of Ca 2+ homeostasis plays an important role in axon function and integrity (28), whereas acyl-carnitine allow extracellular Ca 2+ to enter axons, leading to abnormal axonal mitochondrial function and the onset of apoptosis (29, 30)

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