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The phase 2 trial showed 17.1% average body weight reduction at 48 weeks with the 4mg dose

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STORAGE Store in a dark and dry place at a temperature below 25 C

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For weight management, Zepbound is indicated for adults with a BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity, as an adjunct to reduced-calorie diet and increased physical activity

Widespread expression of the epidermal growth factor EGFR reduced the inhibition of autophagosome formation by beclin-1 and LC3B, as well as increased rubicon and SQSTM1, which ultimately inhibited cellular autophagy