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For researchers prioritizing maximum bioavailability and established protocol reliability, subcutaneous injection likely remains the preferred method

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The trade-off is time, potentially 18+ months from today

A practical rotation might use different sides of the abdomen, alternate thighs, and reserve the upper arm for times when someone can safely help if your device instructions require it

Most patients see slightly improved HbA1c and slightly more weight loss after the switch, partly because of the steadier pharmacokinetics