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Why blends introduce uncertainty No ratio transparency: even if a supplier claims 2.5 mg + 2.5 mg, you cant confirm distribution is uniform after lyophilisation

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Encapsulation into nanoparticles To enhance the pharmacological properties of the metal complex and provide cancer selectivity, Ru(II)-OH was incorporated into a polymer backbone that could self-assemble into tumor-targeting nanoparticles

Oncogene 1995