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The therapeutic benefit which may accompany the higher doses should therefore be weighed against the possibility of a greater incidence of adverse effects

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The Receptor Disappearing Act : Investigators note that neurons with short-lived chemical spikes may be actively degrading or internalizing their own GLP-1 receptors, offering a concrete biological explanation for why many patients eventually hit a weight-loss plateau

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Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action