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For patients with severe obesity (BMI 40 kg/m or 35 kg/m with comorbidities) who have not achieved adequate weight loss with lifestyle and pharmacological interventions, bariatric surgery may be considered

Always discuss the timing of all oral medications and supplements with a licensed professional

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until 2032

Individuals with certain FTO variants show higher natural appetite drive and faster regain after medication stops

Administration and injection technique Retatrutide is administered by subcutaneous injection once weekly