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NNMT inhibitor compound Class: Small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor Formula / M.W.: C 10 H 11 IN 2 , ~286.11 g/mol (iodide salt)

WARNINGS: Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

But those with diets low in animal protein, like vegetarians or vegans, are at high risk for deficiencies

Simultaneously, NNMT inhibition preserves SAM the primary methyl-donor for epigenetic histone and DNA methylation reactions which has been shown to influence gene expression programmes governing adipogenesis, lipid storage, and energy expenditure in adipose tissue models

You are on a vegetarian or vegan diet