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Vitamin B12 deficiency has been linked to fatigue, tingling or loss of feeling in the extremities, irritability, memory impairment, depression, anemia, irritable bowel syndrome (IBS), constipation, poor wound healing, dry or damaged looking skin, and neurological disorders

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The role for GSTs in the detoxification of the reactive metabolite2-ABT-S-oxide (M1) of zileuton, an agent which targets the leukotriene pathway through inhibition of 5-lipoxygenase (5-LO), has been investigated [55]

Ke Z, Tan S, Li H et al (2022) Tangeretin improves hepatic steatosis and oxidative stress through the Nrf2 pathway in high fat diet-induced nonalcoholic fatty liver disease mice