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All of the beneficial effects on appetite control are lost if the medication is stopped." Originally developed for diabetes, GLP-1RAs have shown promise in promoting weight loss by reducing appetite and increasing satiety signals from the gut to the brain

Montrose-Rafizadeh C, Avdonin P, Garant MJ, Rodgers BD, Kole S, Yang H, et al

Individuals with Obesity Those with a BMI over 30, or over 27 with health issues (like high blood pressure), may qualify for GLP-1 treatment for weight loss

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Newer approaches, such as activation of the Takeda G protein-coupled receptor 5 (TGR5