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The positive rat result on CRF-induced corticosterone release (PMID 2995861) sits directly against the negative human result on CRH- and meal-induced ACTH and cortisol (PMID 7777652)

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This study provides a novel perspective to improve our understanding of the mechanism of HUA-associated LVR and provides important information for pharmacological intervention

The peptide also potentially maintains spindle integrity and correct distribution of cortical granules (CG)

This is its greatest strength as a research tool

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