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The study used a reverse translational approach, starting with observations from human use and testing specific mechanisms in controlled animal experiments

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Aside from this lack of difference between the treatment groups, the study had a high dropout rate and, as such, the generalizability of the results of the study should be interpreted with caution

The review concluded with a summary of the current state of knowledge in this field

The agency could also update an interim enforcement policy before final rulemaking, but no such change has been announced for these substances as of July 24