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These nodes demonstrated extensive interactions with other proteins, implying their involvement in modulating metabolic processes such as glycemic control, lipid handling, insulin-related cascades, and inflammatory signaling

Sears SM, Hewett SJ (2021) Influence of glutamate and GABA transport on brain excitatory/inhibitory balance

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This research ultimately led to the development of the first GLP-1 receptor agonist approved for diabetes treatment

Weight loss may continue gradually before plateauing, typically around 12-18 months