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In our study, significant upregulation of Pfetin (KCTD12) was detected in residual tissue from patients with high-grade serous ovarian cancer (HGSOC) who had received neoadjuvant chemotherapy, suggesting a potential role for Pfetin in chemoresistance or tumor aggressiveness

Chronic low-dose cadmium exposure induces liver injury via gut microbiota dysbiosis, even without overt intestinal damage

15 Meanwhile, chronic inflammation driven by intestinal permeability and autoimmunity, and other factors like processed food16and poor sleep, 17 may suppress thyroid activity

Incidentally, ARDS and the cytokine storm characterize the late stages of Covid-19