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Some tests your doctor may order include: Blood and urine tests Chest X-ray PET, MRI, or CT scans to show your brain activity Electroencephalogram (EEG) Spinal fluid analysis Neurological tests for memory Your doctor will use certain criteria to diagnose dementia

Nevertheless, there have been rare reports of people experiencing severe allergic reactions to vitamin B12 supplements

Monitoring: Be aware of any changes in your body and report persistent or worsening side effects to your healthcare provider

Increased MMP-2 and MMP-9 expression and activity can affect BBB permeability by proteolysis of extracellular matrix and structural proteins in brain endothelial cells, increasing the BBB breakdown (Figure 2) (Yang et al., 2007

PMC 2621289

The Journal of Frailty & Aging, 8 (3),154-159