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Skipping can mean the return of cravings ("food noise"), and restarting after a gap may increase side effects

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tricyclic antidepressants, such as amitriptyline (Elavil, Endep)

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doi: 10.1111/acel.14368, 58 HanslmayrS.AxmacherN.InmanC

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Side effects may be more prominent during treatment initiation or dose escalation

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