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In the Phase 3 REDEFINE 1 trial, cagrilintide monotherapy achieved 11.8% average weight loss over 68 weekscomparable to semaglutide but with a notably lower incidence of nausea and vomiting, making it a potential option for patients who dont tolerate GLP-1 medications well
Concentrations and dosing vary depending on experimental design, but common in vitro concentrations range from micromolar to low millimolar levels
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Other risks include pancreatitis, kidney problems, and severe gastrointestinal issues
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