In the SURMOUNT-2 study, which involved 938 adults with obesity or overweight and T2D, tirzepatide showed significant weight loss effects of 13.4% and 15.7% for the 10 and 15 mg doses, respectively, with over 80% of participants experiencing at least a 5% weight loss [92]
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Normally, your stomach empties its contents pretty quickly after you eat
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Moreover, a subgroup analysis revealed that exenatide treatment was numerically better at preventing MACE in patients with a previous history of CV events relative to those without, although there was no statistically significant interaction of the treatment effect across the subgroups [28]
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