Implications of the gut microbiome in Parkinson's disease
This glucose-dependent mechanism is why GLP-1 medications do not cause the dangerous blood sugar lows, hypoglycemia, that were a significant concern with earlier classes of diabetes drugs
Iliceto S, Scrutinio D, Bruzzi P, et al
Despite their current dominance, GLP-1R agonists are not the only contributors to future growth
Additionally, losing lean mass can make it more difficult to maintain weight loss over the long term (2)
Bruzzi JF, Swisher SG , Truong MT, Munden RF, Hofstetter WL, Macapinlac HA, Correa AM, Mawlawi O, Ajani JA, Komaki RR, Fukami N, Erasmus JJ