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In the former, cysteine comes from the conversion of methionine via a series of enzymatic steps, which is unique to liver cells [25]

Cardiovascular Safety The SELECT trial evaluating cardiovascular outcomes in patients with obesity and established cardiovascular disease demonstrated that serious adverse events were actually lower with semaglutide versus placebo (33.4% vs 36.4%), primarily driven by fewer cardiac disorders (11.5% vs 13.5%)

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[2] More serious symptoms may also occur such as depersonalization, restless legs syndrome, seizures, and suicidal ideation