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A 2015 randomized controlled trial found that 10 grams of Fibersol-2 (the fiber in HUM's product) increased postprandial GLP-1 compared to placebo (Ye et al., Nutrition Research , PubMed)
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This may make it more difficult to find coverage for Ozempic
We also attempted replication analysis in the UK Biobank cohort, although the available data predate the availability of semaglutide or tirzepatide, and hence relied on earlier variants of GLP1 receptor agonists
The main goal of this approach is to reap the metabolic effects of the medication while minimizing the risk of side effects and prioritizing comfort and adherence
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