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The GS-TNB is subsequently reduced by glutathione reductase and -nicotinamide adenine dinucleotide phosphate (NADPH), releasing a second TMB molecule and recycling the GSH
The receptor extracellular domain (ECD) was omitted from the final reported structure because of the relatively low resolution owning to its intrinsic flexibility, which is a general feature in most reported class B GPCRG s complex structures
Dehydration/acute kidney injury: Persistent vomiting or diarrhoea may lead to dehydration and kidney problems