Journal of Medicinal Chemistry 54, 510-524
The primary routes for permeation across the BBBinclude passive diffusion (lipid soluble solutes), ABC transporter efflux, carrier-mediated influx, and receptor-mediated transcytosis (Pandian et al., 2022
The Journal of the American Medical Association published an article in June 2024 proving the point
Hydration & Sleep: Adequate water intake and quality rest optimize hormonal balance, aid recovery, and reinforce metabolic efficiency
AI is also improving clinicians ability to understand patients metabolic health beyond standard measures like blood glucose and A1C
For the right patient, under proper medical care, it can be truly life-changing