Switching to another drug, Mounjaro, didnt help her symptoms
It carries an arginine substitution at position 3 and a 13-amino-acid N-terminal extension, giving it 83 amino acids total versus 70 for native IGF-1
Beck JD, Andreeff M , Haghbin M, Miller D, Good RA, Gupta S
doi:10.1111/dom.13924 Abdul-Ghani M, Puckett C, Adams J, et al
SGLT2 inhibitors are superior in terms of mortality outcomes, yet protection against MACE was similar among GLP-1 RAs and SGLT2 inhibitors.16,17 Also, mortality benefits did not reach statistical significance in the CREDENCE and DECLARE-TIMI 58 trials.19,37 The CREDENCE trial was prematurely terminated because of overwhelming renal and cardiovascular benefits
Discussion In this study we examined three clinical treatments that have the potential to influence methylation and redox regulation pathways as well as positively affect oxidative stress