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Visible weight changes are typically noted at 812 weeks of consistent use

Non-GLP-1 weight loss medications like metformin and bupropion-naltrexone (Contrave) are available as generics and cost $30 to $80/month

Highlights Sodium-glucose cotransporter 2 (SGLT2) inhibitor constitutes a class of oral hypoglycemic agents that reduce blood glucose levels by enhancing glucosuria through inhibiting glucose reabsorption in the proximal tubules of the kidney [1,2]

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Conclusion: Navigating the Complex Landscape As of 2025, the compounding of GLP-1s remains a highly contentious issue

For those taking insulin or sulfonylureas, this may increase hypoglycaemia risk, requiring medication review