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PfGrx shares 39% sequence identity with human Grx1, including a CPYC motif and a semiconserved GGC motif, and is well characterized in vitro and in roGFP2 assays in yeast 14,26,30,35

These bridges are formed by clusters of cysteine, serving to shield the hydrophobic core

J Biol Chem 277(28):2528325289

It can directly scavenge diverse oxidants such as superoxide anion, nitric oxide, hydroxyl radical, and carbon radicals through the oxidation of GSH to its oxidized form, GSSG

Lactylation stabilizes DCBLD1 activating the pentose phosphate pathway to promote cervical cancer progression

Unlike ingredients that sit on the surface, GHK-Cu facilitates Remodeling