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Body mass index (BMI) of 27 or greater with at least one weight-related health condition such as hypertension (high blood pressure), type 2 diabetes mellitus, hypercholesterolemia (high cholesterol), and sleep apnea

In the presence of this kind of transition metals other ROS can be produced (29)

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doi: 10.3389/fphys.2020.00446 95

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