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Ozempic as an add-on to basal insulin and Ozempic 1 mg vs 2 mg Primary endpoint: change in A1C from baseline SUSTAIN 5: add-on basal insulin 1,10,11 In adult patients with type 2 diabetes on basal insulin metformin Mean change in A1C from baseline at Week 30 Mean baseline A1C: SUSTAIN FORTE: Ozempic 1 mg vs 2 mg 1,8 In patients with type 2 diabetes on metformin sulfonylurea Mean change in A1C from baseline at Week 40 Mean baseline A1C: Results for SUSTAIN 5 and SUSTAIN FORTE based on sensitivity analyses of retrieved dropout population
Sublingual and oral forms show similar absorption in most research
Most side effects dont last forever
Peak serum concentrations occur 13 days after injection, and the drug's long half-life means steady-state levels build over weeks of consistent dosing
Dahly EM, Gillingham MB, Guo Z, Murali SG, Nelson DW, Holst JJ, et al
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