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The strongest human clinical evidence is for topical use, including the Leyden 2002 photoaging trial and a 2023 NEEL gel topical study reporting an average 28% increase in skin collagen density at 3 months
Nothing worked as well as Wegovy, which WVU prescribed for her as part of a weight-management plan that also included dieting and exercise
This option is typically suggested when other, less invasive treatments have failed
They may also bring added benefits for long-term health
Administration Considerations Both medications are administered via once-weekly subcutaneous injection
(Lausanne) 11 , 598843 (2020)
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