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The resulting small-molecule free lysate was then concentrated twice to a concentration of 36 mg ml 1 , during which we lost 10,000 cells were initially analysed using FACS

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Further investigation of differential gene expression in -1 cells revealed that the most highly upregulated transcripts in response to liraglutide treatment were INS and IAPP (Figure 4, A and B, and Supplemental Figure 4A

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