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It reduces sleep onset time and increases time spent in slow-wave (deep) sleep
- Discontinue use if any adverse reactions occur and consult a healthcare provider
Key ingredients Shatavari (SRI-81 extract, 300mg): Shatavari ( Asparagus racemosus ) has traditionally been used to support female reproductive health, but more recent research has focused specifically on its role in perimenopause.45 84 In randomized controlled trials, a standardized extract known as SRI-81 the same form used in this product has been associated with improvements in perimenopause-related symptoms, including hot flashes, stress, and overall quality-of-life measures.83 85 The 300mg dose used here matches the amount used in these studies, which helps distinguish it from many supplements that rely on lower doses or non-standardized forms
The decline of NAD + with age results from three converging factors: (1) increased activity of CD38, a NADase whose expression increases with age-related chronic inflammation (inflammaging), (2) reduced biosynthesis via the NAMPT (nicotinamide phosphoribosyltransferase) and NMN pathways, and (3) increased demand for NAD+ by PARP-1 to repair increasing oxidative DNA damage
2000 Mar;19(2):205-21
doi:10.1016/S0140-6736(13)62674-4
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