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By inhibiting osteoblast differentiation of VSMCs, GLP-1RAs can ameliorate phosphate-induced vascular calcification, which is mediated by the AMPK/mTOR pathway or AMPK/receptor activator of nuclear factor kappa B ligand (RANKL), as occurs in the osteoblast differentiation of VSMCs [128, 129]

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These findings suggest a potential increased risk of urologic malignancies with GLP-1 receptor agonists

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Makes You Feel Full : GLP-1 helps promote feelings of fullness, which can help you eat less