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While most GLP-1 shortages resolved in early 2025, regional supply issues can still arise

For instance, a large prospective cohort study of 365,339 MASLD patients with no history of T2DM at baseline found that 8,774 developed T2DM during an 11-year follow-up, thus supporting the notion that MASLD occurs before the onset of diabetes (41)

This seemed to be slightly more common in male respondents, with 67% finding it easy overall, in comparison to 57% of female respondents

The Phase 2b MARIPOSA trial evaluated oral bedtime doses of AD109 in adults with mild to severe OSA and included patients with or without obesity and those with or without prior use of PAP therapy

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