Long-term considerations Short-term results are one thing
Overweight and obesity management (NG246) Appendix P: NICE guideline CG43 [PDF]
However, vitamins may contain higher doses of 50 to 500 mcg and 1,000 to 2,000 mcg tablets are available
Results are typically gradual and progressive
One of the most common inquiries is how long it takes for these injections to work
Conditions associated with elevated B12 levels include: Liver disease : Hepatocellular damage releases stored B12 into circulation, with levels correlating with disease severity in conditions such as cirrhosis, hepatitis, and hepatocellular carcinoma Renal impairment : Reduced kidney function decreases B12 clearance, leading to accumulation Haematological malignancies : Myeloproliferative disorders, acute leukaemia, and polycythaemia vera can elevate B12 through increased production of B12-binding proteins (transcobalamins) Solid tumours : Certain cancers, particularly those affecting the liver or gastrointestinal tract, may elevate B12 levels A specific concern relates to cyanocobalamin in patients with Leber's hereditary optic neuropathy , a rare mitochondrial disorder
