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This broadened inclusion criteria allowed for a more comprehensive understanding of drug effects in high-risk groups and supported the expansion of GLP-1R agonist indications beyond glycemic control to include cardiovascular and renal benefits
The dulaglutide molecule consists of two modified DPP-4 resistant GLP-1(7-37) peptides fused to a modified IgG4 Fc fragment, which protect dulaglutide from proteolytic degradation by DPP-4 (132)
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Effect of age, sex, and morbidity count on trial attrition: meta-analysis of individual participant level data from phase 3/4 industry funded clinical trials
Science 388 , eadf2034 (2025)
Third, the propagated event should retain ferroptosis-specific features
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