Consuming saturated fats raises the risk of cardiovascular disease [90]
The search for safe and effective pharmacologic weight-loss agents began in the late 19th century with the discovery that sheep thyroidextract increased metabolic rate and induced significant weight loss
Lancet 330(8571):13001304 Kushner RF, Calanna S, Davies M, Dicker D, Garvey WT, Goldman B et al (2020) Semaglutide 2.4 mg for the treatment of obesity: key elements of the STEP trials 1 to 5
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Combining alcohol with these medications may cause blood sugars to fall too fast, leading to fainting and dizziness
[5] Patients prescribed GLP-1 agonists often have type 2 diabetes or obesity, conditions independently associated with increased rates of osteoarthritis and other musculoskeletal disorders