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Long-term exposure to pollutants like microplastics (MPs) and DEHP promotes excessive ROS production through the CNR1/CRBN/YY1/CYP2E1 axis, oxidizing YAP1, which ultimately leads to necroptosis and impaired ovarian function in granulosa cells (Wu H

If cost, side effects, supply issues, limited results, or the thought of lifelong medication has you frustrated, weight loss surgery may offer a more durable path forward

10th ed

Other forms of dermatoses reported in association with TNF alpha inhibitors tend to occur less often than psoriasiform eruptions and include eczema, leukocytoclastic vasculitis, lupus erythematosus, and granulomatous dermatitis

12 (533), eaay8071 (2020)

Adherence to lifestyle modifications is crucial