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Glutathione has been the subject of thousands of published articles confirming this critical role in human life and its equally vital role in human health

It is also an essential component for numerous metabolic functions, including acid-base (pH) homeostasis

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Avian Med

Furthermore, APAP exposure significantly depletes glutathione [68], suggesting that repeated exposure to the drug is potentially more hazardous than a single exposure.Although APAP metabolism is well characterized, a high degree of variability in APAP metabolism within the pediatric population has been observed, and the factors affecting this variability are poorly understood [69]