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After losing patent protections on two of its biggest stars, anti-depressant Cymbalta and osteoporosis treatment Evista, Eli Lilly desperately needed Trulicity to be a success when it was launched 10 years ago
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Their conclusion: sleep improvement under DSIP treatment is of little clinical significance. [11] Bes and colleagues in Amsterdam ran a double-blind matched-pairs parallel-groups design in 16 chronic insomniacs and found the statistically significant effects were weak and in part could be due to an incidental change in the placebo group, with subjective sleep quality unchanged
For a closer look at why digestive effects can intensify, our Why GLP-1 Medications Cause GI Issues article is a helpful companion read
What Causes Urinary or Bladder Changes on Mounjaro Injection
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