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Obesity is another risk factor for developing CKD

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By mimicking the action of the GLP-1 hormone, Wegovy helps regulate blood sugar levels, prevent rapid sugar spikes and crashes, and lower insulin levels

That third target in retatrutide may account for the additional weight loss through increased energy expenditure, but it also raises a theoretical concern

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For added nutritional support during treatment, you can also look at the GLP-1 Daily Support supplement