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Aflatoxin B1 requires GST conjugation for detoxification, and GSTM1-null individuals have dramatically reduced capacity to clear it

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Still workable but tighter

Abstract Ferroptosis has long been regarded as a cell-autonomous form of regulated cell death driven by iron-dependent lipid peroxidation

doi: 10.3389/fendo.2023.1133000 Received 28 December 2022 Accepted 13 March 2023 Published 24 March 2023 Volume 14 - 2023 Edited by Silvia Martina Ferrari, University of Pisa, Italy Reviewed by Sabrina Rosaria Paparo, University of Pisa, Italy

For a 200-pound person, thats around 30 pounds