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PlexusDx specializes in precision GLP-1 therapy including compounded semaglutide injection at $189/mo month-to-month, or from $149/mo on the 6-month plan

161 However, these problems have not been shown to have a clear causal relationship with GLP-1RA in the general population, and there is a lack of data specific to the MASLD population, especially in individuals without co-existing T2DM

The SURMOUNT-1 trial, published in the New England Journal of Medicine, randomized 2,539 adults with obesity or overweight to tirzepatide 5 mg, 10 mg, or 15 mg weekly for 72 weeks

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Some evidence suggests GLP-1 might also affect reward pathways in the brain related to food cravings and the pleasure response to eating