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proposed that acrolein plays a key role in altering RBC membrane structure, in turn provoking changes in membrane composition, cytosolic proteins, and osmotic sensitivity
PMID 24918645
Correlating the global signal with the time series of each voxel (Pearsons correlation) yields a whole-brain correlation, which is also considered a weighted form of functional connectivity density [42]
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Similarly, DRP-104 (sirpiglenastat), a glutamine antagonist that indirectly inhibits GLS-driven pathways, is in early-phase evaluation, showing manageable safety and rationale for combination with immunotherapy (atezolizumab) (249253)
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