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Co-administration of PAXLOVID with drugs that are primarily metabolized by CYP3A and CYP2D6 or are transported by P-gp or OATP1B1 may result in increased plasma concentrations of such drugs and increase the risk of adverse events

A., Masheb, R

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This trend extends not only to injectable incretin-based agents and oral THR- receptor agonists, but also to emerging investigational classes that are gaining momentum, such as injectable long-acting fibroblast growth factor 21 (FGF21) analogues (e.g., efruxifermin ) and oral pan-peroxisome proliferator-activated receptor (PPAR) agonists (e.g., lanifibranor )

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