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In DIO mice, a GLP-1R/GIPR co-agonist supplemented by an injection of a GcgR agonist resulted in a greater decrease in body weight and food intake than the co-agonist alone [92]
References Kapoor R, Shome D, Vadera S, Kumar V, Ram MS
Laboratory Handling and Storage Protocols Lyophilized Powder Storage: Store at -20C to -80C in original sealed vial Protect from light exposure and moisture Desiccated storage environment recommended Stability data available for 24+ months at -20C Stability Considerations: Ipamorelin demonstrates excellent stability as a lyophilized powder due to its synthetic amino acid modifications providing protease resistance
This is an extremely promising result because the ALC seems to be getting at the underlying cause of hypothalamic amenorrhea insufficient GnRH pulses from the hypothalamus
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