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Zeng et al., 2024)

Energy and fatigue through nutrition Many GLP-1 users report significant fatigue on semaglutide or tiredness on tirzepatide, especially during the first few weeks

Other effects may be mood improvement, tied more to results

And that brings us to CJC-1295

Both agencies noted that the reports were rare relative to the large number of patients using these medications and that confounding factors, including pre-existing mental health conditions, major lifestyle changes, and concurrent medications, made it difficult to attribute psychiatric symptoms directly to GLP1 treatment

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