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At cohort entry, we excluded patients who were less than 18 years of age, had less than one year of medical history in the database, had no diagnosis of type 2 diabetes, had contraindications such as end stage renal disease or multiple endocrine neoplasia, or had concurrent prescriptions for both a GLP-1 receptor agonist and the comparator drug
QiZYDuanJWangQYaoQZhongQHZhangCYet al
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Proc Am Assoc Cancer Res, 2008
Patients with a dual therapy with metformin and a DPP-4 inhibitor can also receive a further treatment intensification with a SGLT-2 inhibitor or a TZD (7074)
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