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American Journal of Physiology - Endocrinology and Metabolism (2006) 11

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If nausea becomes severe enough to interfere with eating adequate protein or forces you to skip doses, discuss dose reduction or slower escalation with your provider

Documented effects in published research (research-context only) Because MT-2 binds the broader melanocortin receptor family beyond MC1R, published research has characterized a wider range of observed effects in animal models compared to MT-1