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These side effects may affect quality of life and treatment adherence in adolescent patients ( 3.2 Impact of metformin on pregnancy in patients with polycystic ovary syndrome PCOS is a commonly occurring endocrine disorder that primarily affects females of reproductive age and is recognized as one of the leading causes of anovulation and female infertility

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Following a thorough analysis of our previous Phase 2b data and trial design, we believe that with the preferred modified release formulation and future trial design optimization, we can advance a competitive oral GLP-1 molecule into registration enabling studies, with the goal of addressing the present and persistent medical needs of people living with obesity. The ongoing open-label, randomized study is evaluating the pharmacokinetics and safety of immediate- and modified release formulations of danuglipron administered orally in healthy adults 18 years or older

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