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Avoid overusing strong products, and do not mix too many active ingredients without guidance

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Notably, despite being a large polyphenol, curcumin is lipophilic and can cross the bloodbrain barrier at sufficient concentrations to exert effects in the CNS (79)

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It is also about which genes get expressed and which go silent

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Acknowledgments We would like to thank the members of AKs lab for providing intellectual insights into the manuscript

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