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Like I I plan everything
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This includes the potential for expanding specialist weight management services outside of hospitals and allowing access to the drugs through GPs
However, it does not follow the ABCDE of melanoma rule
The most significant concern is additive blood pressure lowering , which could occur when retatrutide is used alongside agents such as: ACE inhibitors or angiotensin receptor blockers (ARBs) commonly prescribed in obesity-related hypertension and diabetic nephropathy Calcium channel blockers which may compound vasodilatory effects Thiazide or loop diuretics where volume depletion may be exacerbated by any natriuretic effects of GLP-1 receptor activation and by gastrointestinal fluid losses Alpha-blockers associated with a higher baseline risk of postural (orthostatic) hypotension Beta-blockers relevant given the modest heart rate increase associated with GLP-1 receptor agonists
Some patients may experience postoperative nausea and vomiting (PONV) when continuing semaglutide perioperatively
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Hypothyroidism itself does not prevent Wegovy use, but thyroid function should be monitored as weight loss may alter levothyroxine requirements
